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. 2019 Jun 21;7:145. doi: 10.3389/fbioe.2019.00145

Figure 1.

Figure 1

Results of the color normalization algorithm and blue ratio image generation for one frame: (A) Original HPF; (B) Blue ratio (BR) image; (C) Mitotic 71 × 71 patch generated with the thresholded version of the BR image; (D) Color normalized HPF; (E) Detection of mitosis centroids using the BR image to validate true positive rate; (F) Non-mitotic 71 × 71 patch generated with the thresholded version of the BR image.