. 2019 Feb 4;28(3):264–272. doi: 10.1159/000497436

Table 3.

Cox regression analysis of factors associated with mortality

Variable	90-day mortality		1-year mortality
	HR (95% CI)	p value	HR (95% CI)	p value
Including CrCl by Cockcroft-Gault
Age (years)	1.041 (0.957–1.133)	0.344	1.026 (0.959–1.098)	0.457
BMI (kg/m²)	1.053(0.914–1.213)	0.475	0.980 (0.861–1.116)	0.765
Active cancer (yes)	85.584 (9.375–781.281)	<0.001^*	45.807 (7.772–270.000)	<0.001^*
CrCl (Cockcroft-Gault, mL/min)	0.948 (0.919–0.979)	0.001^*	0.967 (0.943–0.991)	0.008^*
D-dimer (mg/L)	1.052(1.014–1.091)	0.007^*	1.030(0.998–1.063)	0.069
HDL (mmol/L)	0.188 (0.021–1.659)	0.132	0.384 (0.069–2.148)	0.276
PESI	0.942 (0.892–0.994)	0.029^*	0.965 (0.924–1.008)	0.108

Including eGFR by MDRD
Age (years)	1.097 (1.002–1.201)	0.046^*	1.056 (0.989–1.128)	0.104
BMI (kg/m²)	0.938 (0.824–1.069)	0.338	0.903 (0.801–1.019)	0.099
Active cancer (yes)	84.950 (7.838–920.761)	<0.001^*	30.101 (5.160–175.589)	<0.001^*
eGFR (MDRD, mL/min/m²)	0.952 (0.920–0.985)	0.005^*	0.981 (0.958–1.005)	0.120
D-dimer (mg/L)	1.044(1.009–1.081)	0.014^*	1.023(0.992–1.055)	0.145
HDL (mmol/L)	0.205 (0.023–1.829)	0.156	0.360 (0.063–2.069)	0.252
PESI	0.940 (0.887–0.995)	0.034^*	0.971 (0.929–1.014)	0.184

Including eGFR by CKD-EPI
Age (years)	1.088 (0.994–1.192)	0.068	1.052 (0.984–1.125)	0.139
BMI (kg/m²)	0.943 (0.827–1.075)	0.380	0.909 (0.805–1.025)	0.119
Active cancer (yes)	92.361 (8.111–1,051.775)	<0.001^*	38.757 (6.158–243.948)	<0.001^*
eGFR (CKD-EPI, mL/min/m²)	0.948 (0.915–0.983)	0.003^*	0.971 (0.945–0.998)	0.038^*
D-dimer (mg/L)	1.046(1.010–1.084)	0.012^*	1.025(0.994–1.057)	0.113
HDL (mmol/L)	0.213(0.023–1.937)	0.170	0.399 (0.069–2.297)	0.304
PESI	0.937 (0.884–0.994)	0.031^*	0.965 (0.923–1.010)	0.128

BMI, body mass index; HR, hazard ratio; eGFR, estimated glomerular filtration rate; HDL, high-density lipoprotein; CKD-EPI, Chronic Kidney Disease Epidemiology Collaboration.

p < 0.05.