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. 2019 Jun 21;10:1354. doi: 10.3389/fimmu.2019.01354

Figure 6.

Figure 6

Altered immunophenotype of NK cells from PC patients. (A) Representative FACS profiles showing the expression of CD69, CD57, TIGIT, CD96, TIM-3, and PD-1 (red shaded histograms) on gated NK cells in the healthy control (HC) group, the non-malignant group, and the malignant group. The solid lines indicate the isotype control staining. (B) The MFI of the expression of the indicated receptors on NK cells relative to the MFI of the isotype control (ΔMFI) in the HC group (n = 20), the non-malignant group (n = 20), and the malignant group (n = 20). (C) The MFI of the expression of the indicated receptors on NK cells relative to the MFI of the isotype control on NK cells (ΔMFI) in the HC group (n = 20), the non-malignant group (n = 20), the stage II subgroup (n = 10), and the stage III/IV subgroup (n = 10). Horizontal bars indicate the medians. *P < 0.05 and **P < 0.01; Kruskal-Wallis test.