Fig. 2.

Proteins related to protein quality control (PQC) are highly accumulated whereas photosynthesis-related proteins are significantly reduced in the Arabidopsis var2 mutant. (A) Heat maps showing the expression of PQC-related proteins in var2 as compared with the wild-type (WT). GO analysis of the proteins highly accumulated in var2 compared with the WT revealed a significant enrichment in protein folding, proteolysis, detoxification, and chloroplast organization processes (Supplementary Fig. S2A). A complete GO analysis of proteins accumulated in var2 is shown in Supplementary Table S4. (B) Heat maps showing the expression of photosynthesis-related proteins in var2 as compared with the WT. GO analysis of the proteins reduced in var2 revealed a significant enrichment of proteins involved in photosynthetic protein import, PSI and PSII assembly, PSII repair, photosynthetic electron transport chain (PETC), and chlorophyll biosynthesis (Supplementary Fig. S2B). A complete GO analysis of down-regulated proteins in var2 is shown in Supplementary Table S6.