TABLE 2.

Comparison of IVIM imaging parameters acquired from the combinations of 10 b-values and 4 b-values in datasets of untreated and BmK AGAP-treated groups and at various image acquisition time points (data are presented as means ± SDs and were compared using paired t-tests, ^*P < 0.05).

	Day 0 (n = 6)			Day 3 (n = 6)			Day 6 (n = 6)			Day 9 (n = 6)			Day 12 (n = 6)
	10 b-values	4 b-values	P-value	10 b-values	4 b-values	P-value	10 b-values	4 b-values	P-value	10 b-values	4 b-values	P-value	10 b-values	4 b-values	P value
Dslow (10–3mm2/s)
Untreated	0.479 ± 0.214	0.37 ± 0.042	0.533	0.83 ± 0.622	0.776 ± 0.402	0.785	0.509 ± .105	0.535 ± 0.041	0.664	0.517 ± 0.096	0.395 ± 0.064	0.476	0.617 ± 0.155	0.354 ± 0.029	0.208
BmK AGAP	0.554 ± 0.326	0.643 ± 0.132	0.633	1.098 ± 0.540	0.985 ± 0.016	0.821	0.745 ± 0.418	0.66 ± 0.276	0.552	0.712 ± 0.521	0.779 ± 0.497	0.155	0.745 ± 0.309	0.722 ± 0.267	0.585
Dfast (10–3 mm2/s)
Untreated	73.5 ± 2.121	51.15 ± 13.506	0.226	31.75 ± 6.151	67.35 ± 27.507	0.255	21.34 ± 18.752	58.4 ± 39.881	0.536	60.5 ± 7.354	43.1 ± 14.001	0.168	73.5 ± 0.99	64.55 ± 4.596	0.265
BmK AGAP	70.55 ± 58.619	59.25 ± 36.416	0.603	49 ± 5.657	74.05 ± 23.688	0.440	24.45 ± 1.485	86.35 ± 23.547	0.157	56.2 ± 2.687	71.5 ± 40.164	0.702	55.5 ± 8.98	55,95 ± 47.588	0.998
PF (%)
Untreated	41.55 ± 15.627	35.1 ± 3.96	0.578	25.9 ± 4.808	39.35 ± 5.303	0.017*	45.35 ± 9.829	36.0 ± 2.121	0.336	54.65 ± 5.162	35.65 ± 3.465	0.198	61.55 ± 7.001	27.7 ± 0.424	0.098
BmK AGAP	43.85 ± 37.83	33.0 ± 10.607	0.805	14.6 ± 0.283	29.05 ± 12.374	0.340	52.55 ± 5.162	35.9 ± 0.283	0.145	40.585 ± 7.757	24.6 ± 10.889	0.439	37.8 ± 2.121	25.6 ± 17.536	0.313