Table 1. Experimental Reports of Enhanced Enzyme Diffusion.

enzyme	native form	Mw (kDa)	kcat (s–1)	D0 (μm2/s)	De,max (μm2/s)	D/D0	method	ref
urease (jack bean)	hexamer	544	2 × 104	31.8	40.6	1.28	FCS	(4, 5)
catalase (bovine liver)	tetramer	250	5.8 × 104	61a	79	1.3	FCS	(5)
alkaline phosphatase from bovine intestinal mucosa	dimer	160	1.4 × 104	NMb	NM	1.8	FCS	(5)
acetylcholinesterase (E. electricus)	four different forms	430 (8S), 780 (14S), 1100 (18S), 280 (11S)	NM	22	27	1.23	STED-FCS	(6)
hexokinase (Saccharomyces cerevisiae)	dimer	110	200	72.4c	106	1.46	FCS	(35, 36)
aldolase (rabbit muscle)	tetramer	158	5	42.6	56	1.31	FCS	(25)
α subunit of F1-ATPase	monomer	58.7		56.4	64.5	1.14	light scattering	(7)
F1-ATPase (Escherichia coli)	α3β3γδε complex	381d38	∼100d39	33	41	1.24	FCS	(40)

^aThe diffusion coefficient of catalase was measured to be 41 μm²/s by Sumner.⁴¹

^bNM: not mentioned.

^cThe diffusion coefficients of hexokinase monomer and dimer were measured to be 74.6 and 56.4 μm²/s, respectively.⁴²

^dData from a different reference.