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. 2019 May 15;5(6):939–948. doi: 10.1021/acscentsci.9b00228

Table 2. Rg Changes of Some Enzymes/Proteins upon Substrate Binding.

enzyme Rg,free (Å) substrate (or ligand) Rg,bound (Å) Rg,free/Rg,bound ref
lobster arginine kinase 21.15 ± 0.15 arginine + Mg-ADP 19.95 ± 0.2 1.06 (83)
l-arabinose-binding protein 20.86 ± 0.21 l-arabinose 19.90 ± 0.21 1.05 (84)
yeast hexokinase (II isozyme, monomeric) 24.73 ± 0.19 glucose 23.78 ± 0.14 1.04 (85)
  24.73 ± 0.19 glucose 6-phosphate 23.48 ± 0.20 1.05 (85)
human glucokinase (hexokinase IV) 25.9 glucose + AMP-PNP 24.5 1.06 (86)
creaine kinase from mitochondria 55.6 ± 0.9 Mg-ATP 48.9 ± 0.5 1.14 (87)
  55.6 ± 0.9 creatine 55.1 ± 1.1 1.01 (87)
creaine kinase from muscle 28.0 ± 0.4 Mg-ATP 25.6 ± 0.4 1.09 (87)
  28.0 ± 0.4 creatine 28.3 ± 0.6 0.99 (87)
  28.0 ± 0.4 glucose 6-phosphate 23.48 ± 0.14 1.05 (87)
A1-ATPase from Methanosarcina mazei Gö1 50.2 ± 1 Mg-ADP 52.3 ± 1 0.96 (88)
  50.2 ± 1 Mg-ATP 51.4 ± 1 0.98 (88)
  50.2 ± 1 Mg-AMP-PNP 49.2 ± 1 1.02 (88)
rabbit muscle pyruvate kinase 39.7 ± 0.6 P-enolpyruvate 38.8 ± 0.6 1.02 (89)
  39.7 ± 0.6 l-phenylalanine (inhibitor) 40.6 ± 0.4 0.98 (89)
yeast malate synthase 39.6 ± 0.2 acetyl-CoA 38.1 ± 0.01 1.04 (90)
  39.6 ± 0.2 acetyl-CoA + pyruvate 38.0 ± 0.02 1.05 (90)
yeast phosphoglycerate kinase 23.34 ± 0.22 Mg-ATP + 3-phosphoglycerate 22.25 ± 0.26 1.05 (91)
  23.34 ± 0.22 Mg-ATP 22.76 ± 0.24 1.03 (91)
  23.34 ± 0.22 3-phosphoglycerate 23.04 ± 0.45 1.01 (91)