Effect of ROF on histopathological features of Cd-intoxicated heart tissues with Haematoxylin and Eosin (H & E, 100X), Masson Trichrome (MT, 100X) and Periodic Acid–Schiff (PAS, 100X) staining. Photomicrographs of heart tissues of (A) normal control rats, (B) CD- intoxicated rats, (C) ROF treated at low dose (0.5 mg/Kg), and (D) ROF treated at high dose (1.5 mg/Kg). In figures, abbreviation “C” indicates for congestion and “N” for necrosis. Arrows in H&E stained figures, indicates degenerative marks of myocardiocytes, in PAS stained figures, indicate PAS positive materials while in MT stained figures, indicate collagen fibers.