Fig. 8.

Behavioral deficit improvement after hSSC transplantation. a Hindlimb stepping in the cylinder in normal (n = 10), hSSC-transplanted (n = 8), and mock (saline-injected, n = 6) mice at 7 weeks postoperation. b Contact time in normal (n = 10) and hSSC-transplanted (n = 8), and mock (saline-injected, n = 5) mice at 7 weeks postoperation. “*” and “#” represent p < 0.05 compared to mock and normal, respectively. c, d Distance traveled in unit time and movement velocity in normal (n = 10), hSSCs-transplanted (n = 8), and mock (saline-injected, n = 6) mice at postoperation. e Errors per step in the challenging beam of the abovementioned mice at 7 weeks postoperation. f Mean errors at different beam widths. g The number of amphetamine-induced rotation in hSSCs groups, compared to that of the control group (mock). “*” and “**” represent p < 0.05 and p < 0.01, respectively, compared to mock. Each animal received at least five trials. “#” and “##” represent p < 0.05 and p < 0.01, respectively, compared to normal