Table 2.
Parameters of APTT waveform in patients with and without DIC and healthy volunteers
| HV | Without DIC | Pre-DIC | DIC | Without HF | With HF | ||
|---|---|---|---|---|---|---|---|
| 2ndDP | Time (seconds) |
35.5*** (32.6–37.4) |
43.9 (36.6–52.7) |
54.6* (41.0–71.3) |
63.7*** (47.4–84.9) |
58.8*** (46.2–73.9) |
72.5*** (49.7–110) |
| Height (mabs) |
457** (411–535) |
648 (379–973)) |
460* (191–772) |
151*** (83.2–326) |
286*** (144–427) |
107*** (26.5–148) |
|
| NH (mabs) |
234** (170–255) |
316 (164–499) |
176** (93.2–308) |
66.4*** (39.4–150) |
134*** (61.6–188) |
55.0*** (14.5–64.5) |
|
| Width (sec) |
7.45*** (6.80–8.00) |
12.9 (11.2–16.8) |
17.7** (12.5–24.3) |
15.1* (12.4–20.5) |
15.1* (12.4–20.5) |
21.4*** (12.7–38.2) |
|
| 1stDP | Time (sec) |
38.7*** (36.3–40.8) |
50.2 (41.2–58.6) |
60.5* (45.8–76.4) |
70.7*** (52.1–96.8) |
64.9*** (52.2–81.0) |
78.6*** (51.8–128.2) |
| Height (mabs) |
183*** (144–200)) |
389 (241–544) |
251** (154–358) |
103*** (64.2–208) |
200*** (116–257) |
61.2*** (36.8–93.9) |
|
| Width (sec) |
19.5*** (18.0–20.3) |
65,2 (54.8–72.1) |
65.2 (54.0–195) |
66.5 (56.0–200) |
64.6 (57.6–200) |
75.1 (55.0–200) |
|
| 1/2FFP | Time (sec) |
40.9*** (37.8–42.7) |
52.5 (43.1–61.5) |
61.6* (47.1–78.9) |
75.0*** (54.8–99.3) |
69.1*** (54.8–87.9) |
80.9*** (54.7–142) |
| Height (mabs) |
242*** (207–305) |
462 (338–586) |
328* (271–490) |
265*** (178–371) |
319*** (240–399) |
195*** (170–286) |
2ndDP, second derivative peak; 1stDP, first derivative peak, 1/2FFP, fibrin formation peak; NH, negative height; DIC, disseminated intravascular coagulation; HF, hypofibrinogenemia
Data was shown as median (25–75%tile)
***, p < 0.001, **, p < 0.01 or: *p < 0.05 compared with patients without DIC