Table 8.

Biological processes enriched by down-regulated contigs only found FDP versus T₀ (see blue fraction in Venn diagram Additional file 1: Figure S1). Terms sorted by the number of contributing contigs

GO.ID	Term	Annotated	Significant	Expected	p-value
GO:0006807	nitrogen compound metabolic process	1736	66	53.76	0.03251
GO:1901360	organic cyclic compound metabolic process	1400	55	43.36	0.0299
GO:0009058	biosynthetic process	1439	55	44.57	0.04759
GO:1901576	organic substance biosynthetic process	1374	54	42.55	0.03127
GO:0044249	cellular biosynthetic process	1358	53	42.06	0.03699
GO:0006725	cellular aromatic compound metabolic process	1375	53	42.58	0.0453
GO:1901564	organonitrogen compound metabolic process	620	28	19.2	0.02644
GO:0016043	cellular component organization	466	23	14.43	0.01725
GO:0071840	cellular component organization or biogenesis	499	23	15.45	0.03484
GO:1901566	organonitrogen compound biosynthetic process	451	21	13.97	0.039
GO:0006508	proteolysis	298	18	9.23	0.00495
GO:0022607	cellular component assembly	222	13	6.88	0.02012
GO:0034622	cellular macromolecular complex assembly	127	12	3.93	0.00054
GO:0007017	microtubule-based process	132	12	4.09	0.00076
GO:0006461	protein complex assembly	173	12	5.36	0.00728
GO:0070271	protein complex biogenesis	173	12	5.36	0.00728
GO:0065003	macromolecular complex assembly	189	12	5.85	0.01414
GO:0071822	protein complex subunit organization	189	12	5.85	0.01414
GO:0006082	organic acid metabolic process	226	12	7	0.04764
GO:0019752	carboxylic acid metabolic process	226	12	7	0.04764
GO:0043436	oxoacid metabolic process	226	12	7	0.04764
GO:0006520	cellular amino acid metabolic process	126	10	3.9	0.00554
GO:0051258	protein polymerization	36	9	1.11	1.00E-06
GO:0043623	cellular protein complex assembly	76	9	2.35	0.00052
GO:0006457	protein folding	104	9	3.22	0.00477
GO:0030163	protein catabolic process	118	8	3.65	0.02963
GO:1902582	single-organism intracellular transport	88	7	2.73	0.01889
GO:0044257	cellular protein catabolic process	100	7	3.1	0.03502
GO:0051603	proteolysis involved in cellular protein catabolic process	100	7	3.1	0.03502
GO:1901605	alpha-amino acid metabolic process	58	5	1.8	0.03302
GO:0006270	DNA replication initiation	4	4	0.12	9.00E-07
GO:0006261	DNA-dependent DNA replication	5	4	0.15	4.40E-06
GO:0006839	mitochondrial transport	16	4	0.5	0.00121
GO:0009069	serine family amino acid metabolic process	20	4	0.62	0.00293
GO:0008652	cellular amino acid biosynthetic process	31	4	0.96	0.01461
GO:1901607	alpha-amino acid biosynthetic process	31	4	0.96	0.01461
GO:0071103	DNA conformation change	44	4	1.36	0.04628
GO:0009070	serine family amino acid biosynthetic process	7	3	0.22	0.00094
GO:0031032	actomyosin structure organization	7	3	0.22	0.00094
GO:0000278	mitotic cell cycle	14	3	0.43	0.00828
GO:0006720	isoprenoid metabolic process	14	3	0.43	0.00828
GO:0008299	isoprenoid biosynthetic process	14	3	0.43	0.00828
GO:1903047	mitotic cell cycle process	14	3	0.43	0.00828
GO:0015669	gas transport	16	3	0.5	0.01218
GO:0015671	oxygen transport	16	3	0.5	0.01218