FIGURE 1. Experimental Design and Determination of Minimal Effective Concentration of CaCl2.
(A) The experiment design for the 3 protocols. (B, C) The minimal effective concentration of CaCl2 to suppress ganglionated plexi (GP) function was 0.5 mmol/l. Level 1: stimulating voltage from 10 to 30 V; level 2: 40 to 60 V; level 3: 70 to 90 V; level 4: 100 to 120 V. *p < 0.05 versus baseline (BS) at different stimulation levels. ERP = effective refractory period; M = mol/l; MNP = magnetic nanoparticles; RAP = rapid atrial pacing.