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. 2019 Jun 25;26(1):641–649. doi: 10.1080/10717544.2019.1628116

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© 2019 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 4. — MIAT promotes angiogenesis in AS mice by activating the PI3K/Akt signaling pathway. (A) Detection of VEGF mRNA expression in aorta of mice by RT-qPCR. (B) Detection of VEGF protein expression in mouse aorta by western blot analysis. (C) Expression of VEGF protein in aorta of mice detected by immunohistochemical staining (× 200). N = 5. One-way ANOVA was used for data analysis, and LSD-t test was used for comparison after ANOVA. * p < .05 versus the normal group; # p < .05 versus the AS group.