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Differentially abundant species between baseline (Day 0) and endpoint (Day 21) in the prevention sub-study. (a) Placebo group, (b) NAC group, and (c) CHX group. Differences were identified by linear discriminant analysis (LDA) effect size analysis (LEfSe); LDA score ≥3. NAC: N-acetyl cysteine; CHX: chlorhexidine.
