Table 2.
The top five most common AEs of all the grades and Grade ≥ 3.
| AEs | Any grade | AEs | Grade ≥ 3 | ||||||
|---|---|---|---|---|---|---|---|---|---|
| Event rate (95% CI) | Z value | P value | Statistical method | Event rate (95% CI) | Z value | P value | Statistical method | ||
| Nausea | 0.488 (0.380–0.597) | –0.209 | 0.835 | Random | Neutropenia | 0.360 (0.252–0.485) | –2.187 | 0.029 | Random |
| Diarrhea | 0.467 (0.392–0.543) | –0.862 | 0.389 | Random | Thrombocytopenia | 0.194 (0.101–0.340) | –3.675 | 0.000 | Random |
| Neutropenia | 0.427 (0.306–0.558) | –1.092 | 0.275 | Random | Anemia | 0.184 (0.139–0.238) | –8.866 | 0.000 | Random |
| Fatigue | 0.358 (0.295–0.427) | –3.975 | 0.000 | Random | Febrile neutropenia | 0.133 (0.047–0.325) | –3.216 | 0.001 | Random |
| Thrombocytopenia | 0.329 (0.209–0.477) | –2.244 | 0.025 | Random | Leukopenia | 0.106 (0.022–0.387) | –2.502 | 0.012 | Random |