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Oxycodone-specific antibody titers and DLS. (A) DLS of sKLH and OXY-sKLH batch 1 and 11. (B) Male Holtzman rats (n = 3–17/group) were immunized by IM injection with 60 μg of OXY-sKLH with 90 μg of alum on day 0. Serum was collected on day 7 and oxycodone-specific antibody titers were measured. Data are mean ± SD (C–E) SEC analysis performed on sKLH and OXY-sKLH (batch 1 and 11).
*p < 0.05 compared to batch 1.
