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The PK/PD parameter estimation, and the data are derived from Emax model.
| PK-PD parameter |
E
max
(Log10CFU/mL) |
EC50 |
E
0
(Log10CFU/mL) |
Hill’s slope |
R 2 |
|---|---|---|---|---|---|
| AUC24h/MIC(h) | 2.98×10-04 | 849.68 | −3.35 | 0.33 | 0.87 |
| T>MIC (%) | 4.00×10-06 | 46.93 | −1.07 | 9.66 | 0.49 |
