Table 3. Dose Effects of Lithium Treatment.
| PATIENT # | MOST EFFECTIVE DOSE | MG/KG DOSE | BLOOD LEVELS (MMOL/L) | SIDE EFFECTS OF LI | DURATION OF LI TREAMENT (DAYS) | CGI-I | CONCOMITANT MEDICATIONS |
|---|---|---|---|---|---|---|---|
| 1 | 150/300/150 | 3.9 | 0.6 | NR | 201 | 4 | Risperidone, Zonisamide, Buspirone, Diazepam |
| 2 | ER 450 bid | 5.0 | 0.7 | Lethargy | 973 | 1 | Oxcarbazepine, Mirtazapine, Lorazepam, Atenolol, Lisinopril |
| 3 | ER 450 bid | 5.8 | 0.8 | lethargy, tremors at higher doses | 365 | 5 | Betaine, Clorazepate, Leucovorin, Kapvay |
| 4 | 450/300/450 | 7.7 | 1 | NR | 735 | 1 | Fluphenazine, Clonidine, L-Methylfolate, Atarax |
| 5 | 450 bid | 7.7 | 0.8 | fatigue on tid | 763 | 3 | Acetazolamine, Risperidone, Fluoxetine, Clonidine, Lorazepam, Leucovorin |
| 6 | ER 450/300 bid | 3.9 | 0.2 | NR | 488 | 1 | Clonidine |
| 7 | ER 600 bid | 5.6 | 1 | slight right hand tremor | 743 | 2 | Escitalopram, Adderall, Clorazepate, Rantidine |
| 8 | ER 450 bid | 7.8 | 0.8 | NR | 515 | 2 | Creatin |
| 9 | ER 450 bid | 7.3 | 0.6 | NR | 459 | 2 | None |
| 10 | ER 450 bid | 3.2 | 0.6 | lethargy, increased tics | 999 | 3 | Quetiapine, Fluoxetine |
| 11 | 450/300/300 | 5.0 | 0.7 | NR | 880 | 2 | Fluvoxamine |
| 12 | ER 450 bid | 5.0 | 0.6 | NR | 352 | 1 | Quetiapine, Fluoxetine, Clorazepate, Atenolol |
| 13 | ER 450 bid | 6.3 | 0.4 | behaviors worsened | 186 | 5 | Clobazam, Lacosamide, Vagal nerve stimulator |
| 14 | ER 450 bid | 3.5 | 0.7 | dizziness | 3,768 | 3 | Valproic acid, Propranolol, Quetiapine |
| 15 | ER 450 bid | 6.7 | 0.5 | NR | 330 | 1 | Aripriprazole, Fluoxetine, Atomoxetine, Leucovorin |
| 16 | 300 bid | 5.0 | 0.4 | became tolerant | 367 | 4 | Clonidine, Oxcarbazepine |
| 17 | ER 300 bid | 4.2 | 0.1 | NR | 90 | 4 | Thyroid |
| 18 | 150 tid | 1.2 | 0.3 | lethargy | 81 | 3 | Ziprasidone, Topiramate, Clonidine, Fluvoxamine, Trazodone, Lisdexamfetamine |
| 19 | 300/150/300 | 5.6 | 0.2 | NR | 841 | 2 | Guanfacine, Methylphenidate, Aripiprazole |
Note: NR = none reported.