Fig. 4.

Pro-survival, antioxidant and angiogenesis pathways are activated in Nox4^KI mice at baseline.

Gene expression analysis of pro-survival (Nrf2, Bcl2) and antioxidant pathway (Gstα, Nqo1) genes at baseline. The gene expression level for each gene is normalized to the housekeeping gene Rplp0 (A). Representative Western blot images of proteins involved in the cell survival, angiogenesis and fibrosis processes. Quantitation of Western blot experiments are shown in (B).