Fig. 7.

Constitutive Nox4 expression in renal tubular cells does not prevent fibrotic disease progression.

A, B, E: Representative images of Sirius red staining and quantification on the sections of Wt and Nox4^KI kidneys harvested 3 days (A, E) and 10 days (B, E) after subjecting to UUO. Endomucin immunostaining and quantification on the sections of Wt and Nox4^KI kidneys harvested 3 days (C, F) and 10 days (D, F) after subjecting to UUO are presented. The non-obstructed kidneys were used as controls. . (For interpretation of the references to color in this figure legend, the reader is referred to the Web version of this article.)