Table 1.
Sample characteristics: datasets included in the present study by country of origin and stratification of the number of isolates by isolation year, susceptibility testing and drug resistance.
| Country of origin | Isolation year |
No. of isolates with DST (first/s line) | No. of drug resistant isolates (%) |
||||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1995 | 1996 | 1997 | 1998 | 2003 | 2005 | 2006 | 2007 | 2008 | 2009 | 2010 | 2011 | 2012 | 2013 | 2014 | 2015 | 2016 | INH | RIF | STR | EMB | PZA | MDR | XDR | ||
| Angola (n = 89) | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 89 | 0 | 0 | 89/0 | 17 (19.1) | 6 (6.7) | 13 (14.6) | 5 (5.6) | 5 (5.6) | 5 (5.6) | – |
| Brazil (n = 964) | 0 | 0 | 0 | 0 | 0 | 0 | 50 | 65 | 37 | 38 | 71 | 123 | 202 | 161 | 149 | 46 | 22 | 713/48 | 386 (54.1) | 275 (38.6) | 67 (15.6) | 29 (6.7) | 4 (4.4) | 269 (37.7) | 0 (0) |
| Guinea-Bissau (n = 13) | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 13 | 0 | 0 | 0 | 0 | 13/9 | 9 (69.2) | 9 (69.2) | 6 (46.2) | 7 (53.8) | 7 (53.8) | 9 (69.2) | 0 (0) |
| Mozambique (n = 14) | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 14 | 0 | 0 | 0 | 0/0 | – | – | – | – | – | – | – |
| Portugal (n = 367) | 1 | 1 | 5 | 2 | 2 | 3 | 3 | 36 | 91 | 114 | 42 | 35 | 10 | 4 | 7 | 10 | 1 | 367/98 | 174 (47.4) | 67 (15.6) | 150 (40.9) | 97 (26.4) | 112 (31.2) | 140 (38.1) | 40 (40.8) |
| Total (n = 1447) | 1 | 1 | 5 | 2 | 2 | 3 | 53 | 101 | 128 | 152 | 113 | 158 | 225 | 179 | 245 | 56 | 23 | 1182/155 | 586 (49.6) | 434 (36.7) | 236 (26.3) | 138 (15.4) | 128 (23.2) | 423 (35.8) | 40 (25.8) |