Table 3.
Fold regulation in the serum of 12 selected microRNAs (out of the 44 initially assessed).
| microRNA ID | Fold regulation compared to Control | ||
|---|---|---|---|
| ZEN low | ZEN medium | ZEN high | |
| ssc-miR-1 | −3.74 | 2.78 | 1.35 |
| ssc-miR-129a | −1.15 | −2.32 | −3.43 |
| ssc-miR-135a-5p | 2.04 | 7.67 | 2.70 |
| ssc-miR-181c | 1.74 | 3.45 | 1.78 |
| ssc-miR-182 | −1.43 | 1.05 | −2.17 |
| ssc-miR-206 | −3.30 | 2.36 | −2.65 |
| ssc-miR-432-5p | −6.97 | −3.50 | −1.87 |
| ssc-miR-455-3p | −1.58 | 1.43 | 1.42 |
| ssc-miR-455-5p | −1.01 | 2.62 | 1.85 |
| ssc-miR-493-3p | −2.41 | −2.46 | −1.98 |
| ssc-miR-503 | 1.61 | 2.51 | 1.09 |
| ssc-miR-542-3p | 1.05 | 2.56 | 3.32 |
MicroRNAs highlighted in bold showed trend or significance in at least one of the ZEN groups compared to the Control (Fisher’s LSD test done on delta Cq with p < 0.1). The fold regulation is indicated for each experimental group with n = 6 for all groups, except n = 5 for ZEN low (excluded due to high hemolysis in one serum sample).