Table 2.
Odds ratio (OR) of dengue illness with a specific serotype according to the immune status at the beggining of each year.
| Serotype 1 | |||||||
| Heterologous titres | |||||||
| Homologous titre | <10 | [10,20[ | [20,40[ | [40,80[ | [80,160[ | ≥160 | |
| <10 | 1.00 | 3 3.05* | 3 1.36 | 3 1.05 | 3 0.87 | 3 1.32 | |
| [10,20[ | 0.00 | 0.00 | 0.00 | 0.00 | 2 1.38 | 3 0.50 | |
| [20,40[ | 0.00 | 0.00 | 0.00 | 0.00 | 2 3.62 | 3 0.89 | |
| [40,80[ | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 3 0.52 | |
| [80,160[ | 0.00 | 2 0.00 | 0.00 | 0.00 | 0.00 | 3 0.49 | |
| ≥160 | 0.00 | 2 0.00 | 3 0.66 | 2 0.00 | 2 0.00 | 3 0.13* | |
| Serotype 2 | |||||||
| Heterologous titres | |||||||
| Homologous titre | <10 | [10,20[ | [20,40[ | [40,80[ | [80,160[ | ≥160 | |
| <10 | 1.00 | 2 4.28+ | 3 0.51 | 3 1.22 | 3 2.57 | 3 2.57 | |
| [10,20[ | 0.00 | 38.06* | 0.00 | 2 5.77* | 2 5.77* | 3 1.97 | |
| [20,40[ | 0.00 | 0.00 | 0.00 | 2 4.23 | 2 0.00 | 3 1.81 | |
| [40,80[ | 2 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 3 0.75 | |
| [80,160[ | 3 0.00 | 3 0.00 | 0.00 | 0.00 | 0.00 | 3 2.87+ | |
| ≥160 | 3 0.00 | 3 0.00 | 3 0.00 | 3 0.00 | 2 0.00 | 3 0.00 | |
| Serotype 3 | |||||||
| Heterologous titres | |||||||
| Homologous titre | <10 | [10,20[ | [20,40[ | [40,80[ | [80,160[ | ≥160 | |
| <10 | 1.00 | 2 2.71 | 3 2.24 | 3 1.20 | 3 2.85 | 3 1.47 | |
| [10,20[ | 0.00 | 0.00 | 2 0.00 | 2 9.07* | 3 4.98* | 3 3.96+ | |
| [20,40[ | 0.00 | 0.00 | 0.00 | 0.00 | 2 0.00 | 3 3.96* | |
| [40,80[ | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 3 2.80 | |
| [80,160[ | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 3 0.00 | |
| ≥160 | 0.00 | 2 0.00 | 3 0.00 | 3 0.00 | 2 0.00 | 3 0.00 | |
| Serotype 4 | |||||||
| Heterologous titres | |||||||
| Homologous titre | <10 | [10,20[ | [20,40[ | [40,80[ | [80,160[ | ≥160 | |
| <10 | 1.00 | 4.34 | 2 2.30 | 3 5.42* | 3 0.50 | 3 1.89 | |
| [10,20[ | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 3 1.45 | |
| [20,40[ | 2 0.00 | 0.00 | 0.00 | 0.00 | 39.08* | 3 0.00 | |
| [40,80[ | 3 0.00 | 2 0.00 | 0.00 | 0.00 | 0.00 | 3 3.35 | |
| [80,160[ | 0.00 | 2 0.00 | 0.00 | 0.00 | 0.00 | 3 0.00 | |
| ≥160 | 2 0.00 | 0.00 | 2 0.00 | 0.00 | 0.00 | 3 0.00 | |
The heterologous titres refer to the maximum PRNT50 titre measured across the non-homologous titres (e.g. for serotype 1, the heterologous titre is the maximum of the PRNT50 titres against DENV2–4). The numbers on the top left corner of each cell represent the degree of evidence, where the degree is equal to 1 if there are insuficient data to extrapolate any meaningful coeficients (sum of cases and non-cases lower than 5). Degree values of 1 are omitted here for clarity. The degree of evidence is equal to 2 when the sum of cases and non-cases between 5 and 10 and translates to estimated coefficients with not enough data for significance. Degree values of 3 indicates coefficients for which there were enough data for statistical significance (sum of cases and non-cases greater than 10).
+significant at p < 0.1; *significant at p < 0.05; **significant at p < 0.01