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. 2019 Jun 28;9:172. doi: 10.1038/s41398-019-0506-6

Fig. 1. A scheme of the experimental timeline.

Fig. 1

The fMRI sessions followed test for escape behavior one week later. They included the baseline preinjection fMRI measurement (scan 1) acquired 20 min after the start of domitor continuous infusion, i.e., after stabilization of respiratory and cardiac rhythms, and the second fMRI scan at 30 min a"fter ketamine/saline injection (scan 2). After 48 h we repeated the measurement (scan 3). NC - negative cognitive state strain, PC - positive cognitive state strain. The image of the rat in operant box is reproduced from “Neurobiologie depressiver Störungen” by Psychiatrie und Psychotherapie Up2date 2010, with permission from Georg Thieme Verlag.