Fig. 7.

GMAP210 tethering activity controls LAT recruitment at the immune synapse. a, b Confocal images (left panels) and quantification (right panels) of the enrichment of LAT (a, b) at the immune synapse (depicted by the dotted white line) in Jurkat “mean cells” expressing GFP alone, GMAP210-GFP, or different GMAP210 domains coupled to GFP and interacting for 30 min with Raji cells left unpulsed (−, unactivated state) or pulsed with SEE (+, immune synapse formation). N = number of cells constituting the mean image. Horizontal line represents median. **P < 0.01, ***P < 0.001, ****P < 0.0001, ns: non-significant (one-way ANOVA). Data are representative from two independent experiments