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. Author manuscript; available in PMC: 2020 Apr 1.
Published in final edited form as: Genet Epidemiol. 2019 Jan 4;43(3):300–317. doi: 10.1002/gepi.22181

Table 10.

Empirical analysis for the nAL-2 null hypothesis for pedigree P4, sample size nfamilies=1,000 and marker minor allele frequency of 30%. The first two columns report the empirical mean and empirical variance of the z-scores for the five association tests. The last three columns report the proportion of association p-values below a specific significance level. All results based on 100,000 replicates.

emp. mean z emp. variance z α = 0.05 α = 0.01 α = 0.001

FBAT 0.0005 1.0469 0.0555 0.0115 0.0012
FBAT-ev 0.0007 1.0003 0.497 0.0098 0.0008
GDT 0.0016 1.0399 0.0549 0.0122 0.0012
GDT-PO 0.0016 1.0399 0.0549 0.0122 0.0012
PDT - - - - -