Table 16.
Power analysis for pedigree P4. The last five columns contain the proportion of association p-values below a specific significance level for the five association tests and two different MAFs. All results based on 100,000 replicates.
| Sample size | MAF | Significance level |
FBAT | FBAT-ev | GDT | GDT-PO | PDT |
|---|---|---|---|---|---|---|---|
| 200 | 0.05 | 0.05 | 0.0614 | 0.053 | 0.0579 | 0.0579 | - |
| 0.01 | 0.0125 | 0.0088 | 0.0117 | 0.0117 | - | ||
| 0.001 | 0.0012 | 0.0004 | 0.0009 | 0.0009 | - | ||
| 0.30 | 0.05 | 0.0889 | 0.0877 | 0.0876 | 0.0876 | - | |
| 0.01 | 0.0228 | 0.0212 | 0.0234 | 0.0234 | - | ||
| 0.001 | 0.0034 | 0.0024 | 0.0033 | 0.0033 | - | ||
| 1000 | 0.05 | 0.05 | 0.1081 | 0.1066 | 0.0973 | 0.0973 | - |
| 0.01 | 0.0316 | 0.0303 | 0.0269 | 0.0269 | - | ||
| 0.001 | 0.0048 | 0.0039 | 0.0043 | 0.0043 | - | ||
| 0.30 | 0.05 | 0.2557 | 0.254 | 0.2487 | 0.2487 | - | |
| 0.01 | 0.1013 | 0.0991 | 0.1002 | 0.1002 | - | ||
| 0.001 | 0.0234 | 0.0222 | 0.0231 | 0.0231 | - | ||