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. Author manuscript; available in PMC: 2020 Apr 1.
Published in final edited form as: Genet Epidemiol. 2019 Jan 4;43(3):300–317. doi: 10.1002/gepi.22181

Table 18.

Power analysis for pedigree P6. The last five columns contain the proportion of association p-values below a specific significance level for the five association tests and two different MAFs. All results based on 100,000 replicates.

Sample size MAF Significance
level
FBAT FBAT-ev GDT GDT-PO PDT

200 0.05 0.05 0.0624 0.0618 0.097 0.1062 0.0618
0.01 0.0141 0.0136 0.0277 0.0302 0.0139
0.001 0.0014 0.0012 0.004 0.004 0.0014
0.30 0.05 0.1022 0.1016 0.2312 0.2871 0.1028
0.01 0.0282 0.0271 0.0888 0.1189 0.0283
0.001 0.004 0.0036 0.0184 0.027 0.0037

1000 0.05 0.05 0.118 0.1177 0.2832 0.3533 0.1185
0.01 0.0351 0.0346 0.1212 0.1631 0.036
0.001 0.0055 0.0053 0.0296 0.0436 0.0055
0.30 0.05 0.3222 0.322 0.7747 0.874 0.3234
0.01 0.1405 0.1397 0.557 0.7051 0.1436
0.001 0.0361 0.0357 0.284 0.4261 0.0367