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. Author manuscript; available in PMC: 2020 Apr 1.
Published in final edited form as: Genet Epidemiol. 2019 Jan 4;43(3):300–317. doi: 10.1002/gepi.22181

Table 8.

Empirical analysis for the nAL-2 null hypothesis for pedigree P2, sample size nfamilies=1,000 and marker minor allele frequency of 30%. The first two columns report the empirical mean and empirical variance of the z-scores for the five association tests. The last three columns report the proportion of association p-values below a specific significance level. All results based on 100,000 replicates.

emp. mean z emp. variance z α = 0.05 α = 0.01 α = 0.001

FBAT 0.0005 1.0597 0.0574 0.0122 0.0015
FBAT-ev 0.0005 1.001 0.0502 0.01 0.0011
GDT −0.0052 1.0273 0.0539 0.0124 0.0013
GDT-PO −0.0021 1.0595 0.0578 0.0129 0.0017
PDT −0.0021 1.0011 0.0508 0.0104 0.0011