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. 2019 Jun 24;30(2):146–164.

Table 1.

miRNAs discriminating benign vs. malignant thyroid lesions from FNAB samples

Authors Panel of markers Groups n (sample number) Sensitivity (%) Specificity (%) Diagnostic accuracy (%)
Stokowy et al. 2016 miR-484,
miR-184b-3p
mutation-negative follicular thyroid carcinomas and follicular thyroid adenomas 44 89 87 na
Paskas et al. 2015 BRAF V600E,
miR-221,
miR-222,
galectin-3
benign vs. malignant thyroid nodule 120 73.5 89.8 75.7
Panebianco et al. 2015 miR-146b,
miR-222,
KIT, TC1
benign vs. malignant thyroid nodule 118 92.3 94.7 96
Shen et al. 2012 miR-146b,
miR-221,
miR-187,
miR-30d
benign vs. malignant thyroid nodule 68 88.9 78.3 85.3
Keutgen et al. 2012 miR-328,
miR-222,
miR-21,
miR-197
benign vs. malignant thyroid lesions 72 100 86 90
Mazeh et al. 2012 miR-21,
miR-31,
miR-146b,
miR-187,
miR-221,
miR-222
benign vs. malignant thyroid nodule 11 88 100 90