Table 2.
Univariate analysis of perioperative variables
| Factors | Anastomotic leakage (+) n = 30 |
Anastomotic leakage (−) n = 258 |
Total n = 288 |
P |
|---|---|---|---|---|
| Preoperative WBC (109/L, mean ± SD) | 5.8 ± 2.2 | 5.3 ± 1.8 | 5.6 ± 2.3 | 0.92 |
| Preoperative PLT (109/L, mean ± SD) | 279.5 ± 110.7 | 252.4 ± 71.3 | 265 ± 98.8 | 0.833 |
| Preoperative albumin (g/L, mean ± SD) | 35.2 ± 4.6 | 38.9 ± 4.6 | 37.7 ± 4.4 | 0.067 |
| Preoperative CRP (mg/L, mean ± SD) | 0.63 ± 1.3 | 0.75 ± 1.1 | 0.69 ± 0.9 | 0.782 |
| Preoperative HGB (g/L, mean ± SD) | 122.9 ± 17.1 | 128.3 ± 17.6 | 124.9 ± 17.2 | 0.226 |
| Neoadjuvant therapy | 15 (50.0) | 72 (27.9) | 87 (30.2) | 0.013 |
| Postoperative application of albumin | 16 (53.3) | 110 (42.6) | 126 (43.8) | 0.264 |
| Postoperative TPN starting time | 0.158 | |||
| ≤ 24 h | 16 (53.3) | 103 (39.9) | 119 (41.3) | |
| > 24 h | 14 (46.7) | 155 (60.1) | 169 (58.7) | |
| Time to oral feeding (day, mean ± SD) | 5.4 ± 2.3 | 5.4 ± 2.7 | 5.4 ± 2.5 | 0.915 |
| Time to first flatus (day, mean ± SD) | 5.8 ± 4.3 | 5.3 ± 2.3 | 5.5 ± 2.7 | 0.369 |
| Postoperative hospital stay (day, mean ± SD) | 20.3 ± 8.2 | 11.1 ± 4.6 | 11.6 ± 6.7 | < 0.001 |
WBC white blood cell, PLT platelet, CRP c-reaction protein, TPN total parenteral nutrition, SD standard deviation