Fig 1.

Box-and-whisker plots showing the distributions of T1WI signal intensities and skewness of COLLAGE entropy values for pure and different grades of CRN for primary and metastatic cases, respectively. A and B, The signal intensities in primary and metastatic cases, respectively. C and D, The COLLAGE skewness values for the same cases. C, The green star and circle represent the cases from site 2 with 75% CRN and 30% CRN, respectively. D, The green star represents the case from site 2 with 50% CRN. P values for the pairs of groups exhibiting statistically significant difference are also shown.