Table 3.
Association between characteristics of parous women and NAFLD at 25 years: unadjusted and multivariable adjusted odds ratios (95% Cl).
Characteristic | Unadjusted OR (95% CI) |
p value | Multivariable*
OR (95% CI) |
p value |
---|---|---|---|---|
Age (per 5 year) | 1.38 (0.94–2.02) | 0.10 | ||
White race (vs. Black) | 1.29 (0.74–2.25) | 0.37 | 2.36 (1.24–4.50) | 0.01 |
Total post-baseline parity (per birth)† | 0.66 (0.46–0.97) | 0.03 | 0.75 (0.51–1.11) | 0.15 |
BMI (per 3 kg/m2 increase) | 1.25 (1.10–1.43) | <0.01 | 1.30 (1.13–1.50) | <0.01 |
Education >high school vs. ≤high school | 0.76 (0.39–1.49) | 0.43 | ||
Lactation duration (0–1-month reference) | ||||
>1 to 6 months | 0.91 (0.47–1.78) | 0.79 | 0.84 (0.42–1.70) | 0.64 |
>6 months | 0.48 (0.25–0.94) | 0.03 | 0.46 (0.22–0.97) | 0.04 |
Multivariable model determined by backward stepwise elimination with race, BMI and lactation duration in final model.
Forced into final model to adjust lactation duration for number of post-baseline births.
BMI, body mass index; HOMA-IR, homeostatic model assessment of insulin resistance; NAFLD, non-alcoholic fatty liver disease; OR, odds ratio.