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. Author manuscript; available in PMC: 2020 May 1.
Published in final edited form as: Biochem Pharmacol. 2019 Feb 13;163:493–508. doi: 10.1016/j.bcp.2019.02.013

Table 4:

Model determined association constants for phenol and cyclohexanol binding to HCN1 channels.

Constant DTB-P DTB-CH Fold Change
KC 24.6 ± 4.5 4.6 ± 2.0 5.4
KO 5.5 ± 2.6 3.1 ± 1.5 1.8
Constant DIP-P DIP-CH Fold Change
QC 24.8 ± 4.4 6.5 ± 2.2 3.8
Qo 7.4 ± 2.1 4.2 ± 1.5 1.8
Constant DSB-P DSB-CH Fold Change
JC 0.4 ± 0.3 no effect --
JO 0.1 ± 0.2 no effect --

Constants and their errors have been divided by 104 for clarity.