Fig. 6.

CASC11 promoted the migration and invasion in cervical cancer cells through activating Wnt/β-catenin signaling. HeLa cells were transfected with si-CASC11 or negative control (NC), and treated with LiCl, respectively; HeLa cells were transfected with pcDNA 3.1-CASC11 or control, and treated with Dkk-1, respectively. a Cell migration was examined by Transwell assay, and knockdown of CASC11 inhibited the migration of cells, which could be reserved by LiCl; overexpression of CASC11 promoted the migration of cells, which could be reserved by Dkk-1. b Cell invasion was examined by Transwell assay, and knockdown of CASC11 inhibited the invasion of cells, which could be reserved by LiCl; overexpression of CASC11 promoted the invasion of cells, which could be reserved by Dkk-1. 5 fields was taken with an optical microscope. Data were shown as the mean ± SD of 3 independent experiments. *p < 0.5; **p < 0.01; ***p < 0.001