Table 3.
Intent to Treat and Connection to Health Per Protocol Comparisons of Impact on Hemoglobin A1c (HbA1c) over Time
| Outcome is HbA1c over time | Intent To Treat, N=1022 |
Connection to Health Per Protocol, N=458 |
||
|---|---|---|---|---|
| Variable | Adjusted models Coef (SE) |
p-value | Adjusted models Coef (SE) |
p-value |
| Intercept | 7.5385 (.1941) | <.0001 | 6.6848 (.2368) | <.0001 |
| Age group 17 to 49 50 to 64 65 or greater |
ref .8017 (.1368) −1.2746 (.1449) |
--- <.0001 <.0001 |
Ref .8571 (.1956) −1.057 (.2199) |
--- <.0001 <.0001 |
| Gender - Female | .0881 (.1034) | .3942 | .2259 (.1572) | .1509 |
| BMI (at baseline, centered) | −.0232 (.0070) | .0010 | −0.0436 (.0105) | <.0001 |
| Pulmonary | −.4775 (.2289) | .0371 | ||
| Diabetic retinopathy | .3368 (.1595) | .0348 | ||
| Renal | .4531 (.2587) | .0801 | ||
| Oral diabetic medications | .7150 (.1287) | <.0001 | 0.6452 (.1817) | .0004 |
| Insulin | 1.7418 (.1117) | <.0001 | 1.7147 (.1663) | <.0001 |
| Intervention vs SMS-ED (at baseline) CTH vs SMS-ED CTH + PF vs SMS-ED |
−.0987 (.1551) .0160 (.1524) |
.5245 .9164 |
−0.049 (.3530) 0.6519 (.2300) |
.8891 .0047 |
| HbA1c change per 12 months (slope) SMS-ED CTH CTH + PF |
.1638 (.0853) .3022 (.0756) .1441 (.0721) |
Compared to SMS-ED --- .2243 .8601 |
0.1546 (.0920) 0.0671 (.2255) −0.1640 (.1269) |
Compared to SMS-ED --- .7193 .0422 |
1
SMS-ED = Self-Management Support Education, CTH = Connection to Health, CTH+PF = Connection to Health with Practice Facilitation
2
Overall p-value for group x time: .2724. The overall group x time effect is used to determine whether there are differences in slopes between the three study arms. The coefficients in the table show the actual slopes (SE) for each study arm, along with the p-value for the differences for CTH vs SMS-ED, and CTH+PF vs SMS-ED.