Table 2.
Cell-depleting reagents |
Anti-CD4 |
Anti-CD8α |
Anti-CD8β |
Anti-CD16 |
Anti-CD20 |
Anti-CD1631 |
Anti-CD1691 |
Anti-CD3031 |
Anti-CD336 |
CD3-immunotoxin2 |
Anti-rhesus thymocyte globulin |
Non-depleting reagents targeting cell receptors |
Anti-CD11a |
Anti-CD40 |
Anti-CD45RB |
Anti-CD1151 |
Anti-CD154 |
Anti-CD2791 |
Anti-α4β7 integrin |
TGFβ-Ig |
Reagents targeting soluble mediators |
IFNγR-Ig |
IFNγR-Ig |
Anti-IL-10 |
Anti-IL-15 |
Anti-CCL201 |
In development with lead candidate antibody selected
Manufactured by Dr. Zhirui Wang, Massachusetts General Hospital Table kindly provided by Dr. Keith Reimann