Table 3a.

Overall concordance rates of 24U B-LCL HLA genotypes characterized by NGS compared to consensus NGS genotypes

Group	2-Field Concordance (%)					4-Field Concordance (%)
	Identical	Con-2	Con-3	Con-4	Total	Identical	Con-2	Con-3	Con-4	Total
01	97.97	0.00	1.79	0.00	99.77	75.53	2.96	12.63	5.22	96.34
02	96.59	1.31	1.31	0.26	99.48	84.34	7.61	1.68	5.66	99.29
03	97.90	1.87	0.00	0.23	100.0	69.86	10.75	5.61	11.45	97.66
04	96.00	1.18	0.00	2.82	100.0	75.53	11.76	2.12	9.65	99.06
05	97.66	1.41	0.00	0.94	100.0	78.69	7.26	6.32	7.03	99.30
06	97.96	1.53	0.00	0.51	100.0	82.14	4.08	6.12	7.14	99.49
07	95.08	1.17	0.00	3.28	99.53	76.58	8.67	5.39	7.26	97.89
08	95.08	0.52	0.00	1.55	97.15	70.91	7.27	9.35	8.05	95.58
09	98.61	0.00	0.00	1.39	100.0	95.83	0.00	0.00	3.47	99.31
10	97.42	1.41	0.00	1.17	100.0	79.34	5.63	10.56	3.52	99.06
11	95.75	1.39	0.65	1.11	98.89	76.16	10.72	3.60	7.95	98.43
12	96.77	1.11	0.17	0.68	98.72	75.38	7.13	7.47	8.32	98.30
13	98.59	0.70	0.70	0.00	100.0	78.17	10.33	5.87	5.16	99.53
14	97.25	0.86	1.10	0.31	99.53	64.82	11.08	5.23	14.20	95.32
15	85.00	0.00	0.83	4.58	90.42	69.58	7.08	0.83	12.08	89.58
16	98.24	1.76	0.00	0.00	100.0	82.46	16.18	0.00	1.30	99.94

Abbreviations: Identical denotes unambiguous reference allele and unambiguous NGS allele concordance rates; Con-2 denotes ambiguous reference allele and ambiguous NGS allele matched at one allele; Con-3 denotes ambiguous reference alleles and unambiguous NGS alleles matched at one allele; Con-4 denotes unambiguous reference allele and ambiguous NGS allele matched at one allele.