(A) Schematic of NP generation using the emulsion-evaporation technique. (B) Scanning electron microscopy (left), transmission electron microscopy (middle, right) of PLGA NPs, bar = 200 nm. (C) Histogram of NP size distribution. (D) Average particle size, polydispersity, and (E) zeta-potential of OH-Tam-loaded PLGA(50:50) and PLGA(85:15) NPs.