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. 2019 May 31;9(15):4255–4264. doi: 10.7150/thno.35606

Figure 3.

Figure 3

In vitro and in vivo viability and stability test. (A) Viability of myoblasts (C2C12) in 1 and 3 wt% of NIR-gelatin with fixed amount of HA-ty (1 wt%) for up to 2 weeks. (B) In vitro quantification of signal change of C2C12 labeled with ESNF13 (5 µM) and NIR hydrogel over the time course. NIR hydrogels in 10% FBS were used as control. (C) Real-time longitudinal noninvasive imaging of NIR hydrogel (100 µL) injected into the subcutaneous of nude mice for up to 3 weeks. (D) Quantitative plotting of the in vivo signal reduction of NIR hydrogel over time. Scale bars = 1 cm. Data are representative of n = 3 samples or animals.