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. 2019 Jun 9;9(15):4391–4408. doi: 10.7150/thno.32462

Figure 3.

Figure 3

ZnAs@SiO2 NPs promote apoptosis in HCC cells in vitro. (A) Apoptosis analysis of MHCC97L and Hep3b cells after treatment with PBS, ATO or ZnAs@SiO2 NPs for 24 h. (B, C) Quantification of apoptosis rate of MHCC97L and Hep3b cells after treatment with PBS, ATO, or ZnAs@SiO2 NPs for 24 h. (D) Western blots of cleaved PARP and cleaved Caspase-3 after treatment with ATO or ZnAs@SiO2 NPs at indicated time points. (E, F) Cleaved Casepase3 immunofluorescent staining after treatment with PBS, ATO, or ZnAs@SiO2 NPs at indicated time points in MHCC97L and Hep3b cells. Scale bar, 200 µm. ***, P < 0.001.