TABLE 1.
Comparing the subsample included in the current study with the complete Isle of Wight cohort
| (a) on demographics via proportion tests | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Variables | Complete cohort | Subsample | P-value | |||||||
| Gender (female) | 786; 51.2% (Na = 1536) | 193; 51.3% (N = 376) | 0.99 | |||||||
| Season of birth | ||||||||||
| Winter | 499; 32.5% | 116; 30.9% | 0.78 | |||||||
| Spring | 364; 23.7% | 86; 22.9% | ||||||||
| Summer | 353; 23.0% (N = 1536) | 87; 23.1% (N = 376) | ||||||||
| Low birthweight (yes) | 66; 4.4% (N = 1497) | 17; 4.7% (N = 360) | 0.80 | |||||||
| Socio-economic status | ||||||||||
| Low | 209; 15.4% | 51; 13.8% | 0.73 | |||||||
| Medium | 1037; 76.4% (N = 1357) | 287; 77.6% (N = 370) | ||||||||
| Maternal smoking during pregnancy (yes) | 384; 25.3% (N = 1521) | 75; 20.1% (N = 374) | 0.04 | |||||||
| Parental allergy (yes) | 756; 50.0% (N = 1514) | 206; 55.4% (N = 372) | 0.06 | |||||||
| (b) on allergic sensitizations via proportion tests | ||||||||||
| 10 y (n$; %) |
18 y (n; %) |
|||||||||
| Complete cohort | Subsample | P-value | Complete cohort | Subsample | P-value | |||||
| Allergic sensitization | 279; 26.9% (Nb=1036) | 108; 29.8% (N = 363) | 0.26 | 353; 41.4% (N = 853) | 176; 48.2% (N = 365) | 0.01 | ||||
| Mono-sensitizationc | Female (N = 520) | Male (N = 516) | Female (N = 168) | Male (N = 195) | Female (N = 446) | Male (N = 407) | Female (N = 172) | Male (N = 193) | ||
| Alternaria | 1; 0.19% | 3; 0.58% | 1; 0.60% | 3; 1.54% | 6; 1.35% | 3; 0.74% | 4; 2.33% | 2; 1.04% | ||
| Cladosporium | 1; 0.19% | 1; 0.19% | — | 1; 0.51% | 1; 0.22% | — | — | — | ||
| HDM | 38; 7.31% | 55; 10.66% | 15; 8.93% | 18; 9.23% | 38; 8.52% | 48; 11.79% | 14; 8.14% | 22; 11.40% | ||
| Cat dander | 4; 0.77% | 5; 0.97% | — | 4; 2.05% | 2; 0.45% | 1; 0.25% | — | — | ||
| Dog dander | 2; 0.38% | — | — | — | 1; 0.22% | 1; 0.25% | 1; 0.58% | 1; 0.52% | ||
| Grass | 13; 2.50% | 17; 3.29% | 6; 3.57% | 7; 3.59% | 25; 5.61% | 7; 1.72% | 15; 8.82% | 4; 2.07% | ||
| Cod | — | 1; 0.19% | — | 1; 0.51% | — | — | — | — | ||
| Peanut | — | 1; 0.19% | — | 1; 0.51% | 1; 0.22% | 1; 0.25% | 1; 0.58% | 1; 0.52% | ||
| Totalc | 59; 11.35% | 83; 16.09% | 22; 13.10% | 34; 17.44% | 74; 16.59% | 61; 14.99% | 35; 20.34% | 30; 15.54% | ||
| Poly-sensitizationc | Female (N = 520) | Male (N = 516) | Female (N = 195) | Male (N = 168) | Female (N = 446) | Male (N = 407) | Female (N = 172) | Male (N = 193) | ||
| 59; 11.35% | 77; 14.92% | 20; 11.90% | 32; 16.41% | 83; 18.61% | 129; 31.70% | 42; 24.42% | 68; 35.23% | |||
All Ns denote the number of subjects with no missing values for each variable. In total, N = 376 subjects were included in the analyses.
All Ns denote the number of subjects with no missing values for each variable. In total, N = 376 subjects were included in the analyses.
Number and percentage of subjects mono-sensitized against one allergen for each gender at each age (10 and 18 y), and “Total” refers to the number and percentage of subjects mono-sensitized against one of the 11 allergens, stratified by gender and age. For mono-sensitizations, only allergens with at least one subject with positive SPT at ages 10 or 18 are included in the table.
All n’s denote the number of subjects in each sensitization category, and %’s are calculated by n/N × 100%.