Table 1.
Univariate comparisons between patients with and without cerebellar microbleeds.
| Patient without cerebellar CMBs N=172 |
Patient with cerebellar CMBs N=135 |
p-value | |
|---|---|---|---|
| Age, years (SD) | 70.4 (12.8) | 69.7 (12.6) | 0.6 |
| Sex (female), n (%) | 90 (52.3) | 84 (62.2) | 0.1 |
| Hypertension, n (%) | 121 (70.3) | 117 (86.7) | <0.001 |
| Diabetes, n (%) | 36 (20.9) | 35 (25.9) | 0.3 |
| Hypercholesterolemia, n (%) | 82 (47.7) | 56 (41.5) | 0.3 |
| Warfarin use, n (%) | 19 (11.0) | 28 (20.7) | 0.03 |
| Antiplatelets use, n (%) | 77 (44.8) | 57 (42.2) | 0.7 |
| Presence of supratentorial CMBs, n (%) | 88 (51.2) | 96 (71.1) | <0.001 |
| Lacunes presence, n (%) | 53 (30.8) | 58 (42.9) | 0.03 |
| Severe CSO EPVS > 20, n (%) | 70 (40.7) | 57 (42.2) | 0.8 |
| Severe BG EPVS > 20, n (%) | 36 (20.9) | 35 (25.9) | 0.3 |
| WMH volume mL, median (IQR) | 15 (8.2–29.7) | 24 (11–41.2) | <0.001 |
| cSS presence, n (%) | 13 (7.6) | 18 (13.3) | 0.3 |
| Diagnosis of Probable CAA*, n (%) | 49 (28.5) | 38 (28.1) | 1.0 |
| Diagnosis of Deep/Mixed ICH, n (%) | 72 (41.9) | 78 (57.8) | 0.006 |
SD: standard deviation, CMBs: cerebral microbleeds, CSO: Centrum Semiovale, EPVS: Enlarged perivascular spaces, cSS: cortical superficial siderosis, SVD: small vessel disease, WMH: white matter hyperintensities, IQR: interquartile range, CAA: cerebral amyloid angiopathy.
Probable CAA according to the modified Boston criteria