Table 2.
Univariate comparisons between patients with superficial cerebellar microbleeds and those with deep/mixed cerebellar microbleeds.
| Strictly superficial cerebellar CMBs N= 85 |
Deep/mixed cerebellar CMBs N= 50 |
p-value | |
|---|---|---|---|
| Age, years (SD) | 70.8 (12.1) | 68.1 (13.3) | 0.2 |
| Sex (female), n (%) | 55 (64.7) | 29 (58.0) | 0.5 |
| Hypertension, n (%) | 74 (87.1) | 43 (86.0) | 1 |
| Diabetes, n (%) | 22 (25.9) | 13 (26.0) | 1 |
| Hypercholesterolemia, n (%) | 37 (43.5) | 19 (38.0) | 0.6 |
| Warfarin use, n (%) | 15 (17.6) | 13 (26.0) | 0.2 |
| Antiplatelets use, n (%) | 38 (44.7) | 17 (34.0) | 0.3 |
| Presence of supratentorial CMBs, n (%) | 57 (67.1) | 39 (78.0) | 0.2 |
| Lacunes presence, n (%) | 36 (42.3) | 22 (44.0) | 0.8 |
| Severe CSO EPVS > 20, n (%) | 36 (42.3) | 21 (42.0) | 1.0 |
| Severe BG EPVS > 20, n (%) | 29 (34.1) | 19 (38.0) | 0.2 |
| WMH volume, median (IQR) | 23.6 (6.6-38.0) | 28.9 (12.1-48.7) | 0.3 |
| cSS presence, n (%) | 14 (16.4) | 4 (8.0) | 0.2 |
| Diagnosis of Probable CAA,* n (%) | 30 (35.3) | 8 (16.0) | 0.02 |
| Diagnosis of Deep/Mixed ICH, n (%) | 40 (47.0) | 38 (76.0) | 0.001 |
SD: standard deviation, CMBs: cerebral microbleeds, CSO: centrum semiovale, BG: basal ganglia, CMBs: cerebral microbleeds, EPVS: enlarged perivascular spaces, WMH: white matter hyperintensities, IQR: interquartile range, cSS: cortical superficial siderosis, ICH: intracerebral hemorrhage, CAA: cerebral amyloid angiopathy.