Table 4.

Tigecycline Minimal Inhibitory Concentrations (MICs) in the absence and presence of efflux pump inhibitors.

Strain	TGC	TGC + CCCP	TGC + RES	TGC + VER
	(mg/L)
VRE57	0.060	0.060	0.060	0.030
VRE65	1.000	1.000	1.000	0.250
VRE69	1.000	1.000	1.000	0.250
VRE80	1.000	1.000	1.000	0.250
VRE109	0.060	0.030	0.060	0.030
A1	0.060	0.030	0.060	0.030
A11	0.125	0.125	0.125	0.030
A20	0.500	0.500	0.500	0.060
A42	1.000	1.000	1.000	0.125
B1	0.060	0.060	0.060	0.030
B21	0.250	0.250	0.250	0.030
B42	0.500	0.500	0.500	0.125
C1	0.060	0.030	0.060	0.030
C6	0.125	0.125	0.125	0.06
C42	1.000	1.000	0.500	0.125
VRE109(pAT28)	0.060	N/A	N/A	N/A
VRE109(pAT28-hypVRE80)	0.125	N/A	N/A	N/A
VRE109(pAT28-rpsJVRE80)	0.060	N/A	N/A	N/A
OG1RF(pMSP3535)	0.060	N/A	N/A	N/A
OG1RF(pMSP3535-abcVRE80)	0.060	N/A	N/A	N/A
VRE109(pAT28-marR VRE109)	0.060	N/A	N/A	N/A
VRE109(pAT28-marRB42)	0.125	N/A	N/A	N/A
B42(pAT28)	1.000	N/A	N/A	N/A
B42(pAT28-marRVRE109)	1.000	N/A	N/A	N/A
B42(pAT28-marRB42)	2.000	N/A	N/A	N/A

TGC: tigecycline; CCCP: carbonyl cyanide 3-chlorophenylhydrazone; RES: reserpine; VER: verapamil; N/A: not applicable.