Table 3.
MR imaging protocol |
1.Dixon series: Axial T1-weighted 3-D 2-point Dixon gradient echo sequence capable of generating water-only and fat-only images in addition to in-phase and op-phase images 2.Diffusion-Weighted images (DWI) and ADC map: Axial DW-SS-EPI with two b-values; 0 and 500 mm2/sec; respiratory triggered 3.MRCP images a. 2D thick slab MRCP, 40-mm-thick, 6-8 para-coronal projections to best show the pancreatic duct from different angles b. 3D MRCP: 1 mm respiratory synchronized 3-D turbo spin-echo sequence. c. Secretin-stimulated 2D thick slab MRCP: After IV infusion, the ductal system is imaged via a coronal single-shot turbo spin-echo sequence, repeated every 20 s for 8 min. 4. Pre-contrast T1 mapping: Dual flip-angle spoiled gradient echo (SPGR) technique 5. Obtain B1 map (for compensation of field inhomogeneity) 6. T1-weighted images: 3-D gradient echo with fat suppression: a. pre-contrast b. arterial c. portal venous d. 5-minute delayed phases 7. T2-weighted images with fat suppression: axial 8. T2-weighted images: turbo spin-echo (TSE) or a variant of TSE: axial and coronal, without fat suppression 9. Post-contrast T1 maps 10. MR elastography: MRE will be performed using a passive driver operating at 40 (or 60 Hz). Axial 3D echo planar imaging will be used to acquire images. |
Parameters may change depending on MRI hardware and optimization with phantom tests