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. 2010 Jan 20;2010(1):CD003420. doi: 10.1002/14651858.CD003420.pub4

5.7. Analysis.

Comparison 5 Complications: High dose (Block replace) regimen versus low dose (Titration) regimen, Outcome 7 Drug wthdrawal either group.

Drug wthdrawal either group
Study  
Maugendre 1999 5 out of 175
McIver B 1996 5 out of 111
Rittmaster 1998 16 (12 rash, 2 hepatitis, 1 agranulocytosis, 1GI intolerance) 
 out of 149