Comparison 13.

Interferon versus control ‐ surrogate outcomes ‐ low risk of bias trials

Outcome or subgroup title	No. of studies	No. of participants	Statistical method	Effect size
1 Sustained viral response	1	1050	Risk Ratio (M‐H, Fixed, 95% CI)	18.56 [2.49, 138.50]
2 Failure to achieve a sustained biochemical response	0	0	Risk Ratio (M‐H, Fixed, 95% CI)	0.0 [0.0, 0.0]
3 Improvement in METAVIR activity score	0	0	Risk Ratio (M‐H, Fixed, 95% CI)	0.0 [0.0, 0.0]
4 Progression to cirrhosis	1	622	Risk Ratio (M‐H, Fixed, 95% CI)	0.93 [0.69, 1.25]
5 Improvement in METAVIR fibrosis score	0	0	Risk Ratio (M‐H, Fixed, 95% CI)	0.0 [0.0, 0.0]