Database	Period of Search	Search Strategy
Cochrane Hepato‐Biliary Group Controlled Trials Register	August 16, 2012.	(interferon and 'chronic hepatitis C') AND NOT ('hepatitis B' or HIV or 'human immune deficiency virus' or 'human immunodeficiency virus' or 'liver transplant*')
Cochrane Central Register of Controlled Trials (CENTRAL) in The Cochrane Library	Issue 8, 2012.	#1 MeSH descriptor Interferons explode all trees   #2 (interferon*)     #3 (#1 OR #2)    #4 MeSH descriptor Hepatitis C, Chronic explode all trees    #5 (chronic hepatitis c)     #6 (#4 OR #5)        #7 (#3 AND #6)  #8 (HIV) or (human immunodeficiency virus) or (hepatitis B) or (liver transplant*) or(human immune deficiency virus)    #9 (#7 AND NOT #8)
MEDLINE (OvidSP)	1950 to August 16, 2012.	1. exp Interferons/ 2. interferon*.mp. [mp=title, original title, abstract, name of substance word, subject heading word] 3. 1 or 2 4. exp Hepatitis C, Chronic/ 5. chronic hepatitis c.mp. [mp=title, original title, abstract, name of substance word, subject heading word] 6. 4 or 5 7. 6 and 3 8. (hepatitis B or HIV or human immune deficiency virus or human immunodeficiency virus or liver transplant*).mp. [mp=title, original title, abstract, name of substance word, subject heading word] 9. 7 not 8 10. (random* or blind* or placebo* or meta‐analysis).mp. [mp=title, original title, abstract, name of substance word, subject heading word] 11. 10 and 9
EMBASE (OvidSP)	1945 to August 16, 2012.	1. exp Interferon/ 2. interferon*.mp. [mp=title, abstract, subject headings, heading word, drug trade name, original title, device manufacturer, drug manufacturer name] 3. 1 or 2 4. exp Hepatitis C/ 5. chronic hepatitis c.mp. [mp=title, abstract, subject headings, heading word, drug trade name, original title, device manufacturer, drug manufacturer name] 6. 4 or 5 7. 6 and 3 8. (hepatitis B or HIV or human immune deficiency virus or human immunodeficiency virus or liver transplant*).mp. [mp=title, abstract, subject headings, heading word, drug trade name, original title, device manufacturer, drug manufacturer name] 9. 7 not 8 10. (random* or blind* or placebo* or meta‐analysis).mp. [mp=title, abstract, subject headings, heading word, drug trade name, original title, device manufacturer, drug manufacturer name] 11. 10 and 9
Science Citation Index Expanded (http://apps.isiknowledge.com)	1900 to August 16, 2012.	# 7 #6 AND #5 # 6 TS=(random* or blind* or placebo* or meta‐analysis) # 5 #3 NOT #4 # 4 TS=(hepatitis B or HIV or human immune deficiency virus or human immunodeficiency virus or liver transplant*) # 3 #2 AND #1 # 2 TS=(chronic hepatitis C) # 1 TS=interferon*