Diego 2001.

Methods	RCT (2 groups) MT vs. other
Participants	24 male and female adolescents (13‐19); HIV+, no AIDS symptoms; outpatients.
Interventions	Group 1: MT 12/52 2xpw for 20min (upper body in chair) n=12 Group 2: Other ‐ 12/52 progressive muscular relaxation 2xpw n=12
Outcomes	STAI (anxiety); CES‐D (depression); CD4, CD8 and NKC counts; CD4/8 ratio.
Notes	MT reduced depression (p<0.05); increased NKC number and marker (p<0.01); increased CD4 (p<0.05) compared to other modality.
Risk of bias
Bias	Authors' judgement	Support for judgement
Adequate sequence generation?	Low risk	Sequence generation relayed via email
Allocation concealment?	High risk	Not reported or relayed via email
Blinding? All outcomes	Low risk	Of assessors
Incomplete outcome data addressed? All outcomes	Low risk	living with HIV/AIDS. Cochrane Database of Systematic Reviews 2004,
Free of selective reporting?	Low risk	Most likely
Free of other bias?	Low risk	Baseline characteristics for groups did not differ